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Publications

Journal Articles

 

  1. Akalın, Ali Aykut and Dedekargınoğlu, Barış and Choi, Sae Rome and Han, Bumsoo and Ozcelikkale, Altug, 2022-06-01,
    "Predictive Design and Analysis of Drug Transport by MultiScale Computational Models Under Uncertainty". Pharmaceutical Research . (url)
  2. Pathni, Aashli and Özçelikkale, Altuğ and Rey-Suarez, Ivan and Li, Lei and Davis, Scott and Rogers, Nate and Xiao, Zhengguo and Upadhyaya, Arpita, 2022,
    "Cytotoxic T Lymphocyte Activation Signals Modulate Cytoskeletal Dynamics and Mechanical Force Generation". Frontiers in Immunology 13, . (url)
  3. Moon, Hye-ran and Ozcelikkale, Altug and Yang, Yi and Elzey, Bennett D. and Konieczny, Stephen F. and Han, Bumsoo, 2020-09-02,
    "An Engineered Pancreatic Cancer Model with Intra-Tumoral Heterogeneity of Driver Mutations". Lab on a Chip . (url)
  4. Ozcelikkale, Altug and Shin, Kyeonggon and Noe-Kim, Victoria and Elzey, Bennett D. and Dong, Zizheng and Zhang, Jian-Ting and Kim, Kwangmeyung and Kwon, Ick Chan and Park, Kinam and Han, Bumsoo, 2017-11-28,
    "Differential Response to Doxorubicin in Breast Cancer Subtypes Simulated by a Microfluidic Tumor Model". Journal of Controlled Release 266, : 129–139 . (url)
  5. Ozcelikkale, Altug and Dutton, J. Craig and Grinnell, Frederick and Han, Bumsoo, 2017-10-01,
    "Effects of Dynamic Matrix Remodelling on En Masse Migration of Fibroblasts on Collagen Matrices". Journal of The Royal Society Interface 14, no. 135 : 20170287 . (url)
  6. Wan, Qiaoqiao and TruongVo, ThucNhi and Steele, Hannah E. and Ozcelikkale, Altug and Han, Bumsoo and Wang, Yingxiao and Oh, Junghwan and Yokota, Hiroki and Na, Sungsoo, 2017-08-22,
    "Subcellular Domain-Dependent Molecular Hierarchy of SFK and FAK in Mechanotransduction and Cytokine Signaling". Scientific Reports 7, no. 1 : 9033 . (url)
  7. Liang, Youyun and Clay, Nicholas Edwin and Sullivan, Kathryn M and Leong, Jiayu and Ozcelikkale, Altug and Rich, Max H and Lee, Min Kyung and Lai, Mei‐Hsiu and Jeon, Hojeong and Han, Bumsoo, 2017,
    "Enzyme‐Induced Matrix Softening Regulates Hepatocarcinoma Cancer Cell Phenotypes". Macromolecular Bioscience 17, no. 9 . (url)
  8. Ozcelikkale, Altug and Moon, Hye-ran and Linnes, Michael and Han, Bumsoo, 2017,
    "In Vitro Microfluidic Models of Tumor Microenvironment to Screen Transport of Drugs and Nanoparticles". Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology : e1460-n/a . (url)
  9. Clay, Nicholas Edwin and Shin, Kyeonggon and Ozcelikkale, Altug and Lee, Min Kyung and Rich, Max H. and Kim, Dong Hyun and Han, Bumsoo and Kong, Hyunjoon, 2016-11-14,
    "Modulation of Matrix Softness and Interstitial Flow for 3D Cell Culture Using a Cell-Microenvironment-on-a-Chip System". ACS Biomaterials Science & Engineering 2, no. 11 : 1968–1975 . (url)
  10. Ghosh, Soham and Ozcelikkale, Altug and Dutton, J. Craig and Han, Bumsoo, 2016-10-01,
    "Role of Intracellular Poroelasticity on Freezing-Induced Deformation of Cells in Engineered Tissues". Journal of The Royal Society Interface 13, no. 123 : 20160480 . (url)
  11. Li, Feiran and Cha, Tae-Gon and Pan, Jing and Ozcelikkale, Altug and Han, Bumsoo and Choi, Jong Hyun, 2016-06-16,
    "DNA Walker-Regulated Cancer Cell Growth Inhibition". ChemBioChem 17, no. 12 : 1138–1141 . (url)
  12. Ozcelikkale, Altug and Han, Bumsoo, 2016-01-14,
    "Thermal Destabilization of Collagen Matrix Hierarchical Structure by Freeze/Thaw". PLoS ONE 11, no. 1 : e0146660 . (url)
  13. Kwak, Bongseop and Ozcelikkale, Altug and Shin, Crystal S. and Park, Kinam and Han, Bumsoo, 2014-11-28,
    "Simulation of Complex Transport of Nanoparticles around a Tumor Using Tumor-microenvironment-on-chip". Journal of Controlled Release 194, : 157–167 . (url)
  14. Ozcelikkale, A. and Ghosh, S. and Han, B., 2013,
    "Multifaceted Transport Characteristics of Nanomedicine: Needs for Characterization in Dynamic Environment". Molecular Pharmaceutics 10, : 2111–2126 . (url)
  15. Seawright, Angela and Ozcelikkale, Altug and Dutton, Craig and Han, Bumsoo, 2013,
    "Role of Cells in Freezing-induced Cell-fluid-matrix Interactions within Engineered Tissues". J Biomech Eng 135, : 91001 . (url)
  16. Xu, Z and Ozcelikkale, A and Kim, Y L and Han, B, 2013,
    "Spatiotemporal Characterization of Extracellular Matrix Microstructures in Engineered Tissue: A Whole-Field Spectroscopic Imaging Approach". J Nanotechnol Eng Med 4, : 110051–110059 . (url)
  17. Ozcelikkale, Altug and Sert, Cuneyt, 2012-05,
    "Least-Squares Spectral Element Solution of Incompressible Navier–Stokes Equations with Adaptive Refinement". Journal of Computational Physics 231, no. 9 : 3755–3769 . (url)

 

Conference Presentations

 

  1. Dedekargınoğlu, Barış and Akalın, Ali Aykut and Ozcelikkale, Altug,
    "Rapid Low-Cost Prototyping of Organ-on-Chip Platforms by 3D-Printed Microfluidics". presented at 3rd Annual European Organ-on-Chip Society Meeting, Uppsala, Sweden (Online), 2021-07-01 .
  2. Ozcelikkale, Altug and Upadhyaya, Arpita,
    "Regulation of Cytoskeletal Dynamics during T Cell Activation by Substrate Stiffness". presented at APS March Meeting 2018, 2018-03-07 .
  3. Noe-Kim, Victoria and Ozcelikkale, Altug and Han, Bumsoo,
    "An In Vitro Microfluidic Tumor Model to Mimic Ductal Carcinoma In Situ". presented at The Summer Biomechanics, Bioengineering, and Biotransport Conference, 2015-06-18 .
  4. Ozcelikkale, Altug and Shin, Kyeonggon and Noe-Kim, Victoria and Shin, Crystal S. and Park, Kinam and Han, Bumsoo,
    "Rapid Screening of Anti-cancer Drugs and Delivery Vehicles Using Tumor Microenvironment-on-Chip". presented at 2014 Controlled Release Society Annual Meeting and Exposition, Chicago, IL, 2014-07-15 .
  5. Ozcelikkale, Altug and Elzey, Bennet D. and Ratliff, Timothy L. and Han, Bumsoo,
    "Development of Tumor-On-Chip Platform to Tumor Heterogeneity Induced Chemoresponse". presented at Walther Cancer Foundation Symposium, South Bend, IN, 2013-10-05 .
  6. Ozcelikkale, Altug and Li, Yan and Xu, Xianfan and Han, Bumsoo,
    "Effects of Freezing on Collagen Nanoscale Structure in Engineered Tissues". presented at ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, Boston, 2013 .
  7. Kim, Ah Young and Xu, Zhengbin and Ozcelikkale, Altug and Han, Bumsoo,
    "Functional Imaging of Matrix Structure of Cryopreserved Engineered Tissues Using Back-Directional Gated Mesoscopic Imaging". presented at ASME 2012 Summer Bioengineering Conference, 2012 .
  8. Ozcelikkale, Altug and Han, Bumsoo,
    "Nano-Scale Fluid-Structure Interactions in Cytoplasm During Freezing". presented at Proceedings of ASME 2012 International Mechanical Engineering Congress & Exposition, 2012 .
  9. Seawright, Angela and Ozcelikkale, Altug and Dutton, Craig and Han, Bumsoo,
    "Role of Cells in Freezing-Induced Cell-Fluid Matrix Interactions Within Engineered Tissues". presented at ASME 2012 Summer Bioengineering Conference, 2012 .
  10. Ozcelikkale, Altug and Sert, Cuneyt,
    "H- and p-Adaptive Incompressible Flow Solutions on Cartesian Grids Using Least Squares Spectral Element Method". presented at ECCOMAS CFD 2010 Conference, Lisbon, Portugal, 2010-06 .
  11. Ozcelikkale, Altug and Conteh, Abass and Korc, Murray and Han, Bumsoo,
    "Role of Cancer-Associated Fibroblasts on Drug Response of Pancreatic Cancer Using Tumor-Microenvironment-on-Chip". presented at 2016 Controlled Release Society Annual Meeting and Exposition, .

 

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